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聯(lián)系我時,請告知來自 環(huán)保在線GHBP Bovine/ 重組牛生長激素結合蛋白 產(chǎn)品編號:CYT-471
產(chǎn)品規(guī)格:100μg/200μg/1mg
Synonyms | GHR, GHBP, GH receptor, Somatotropin receptor. |
Introduction | GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized. |
Description | Growth Hormone Binding Protein Bovine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 28 kDa. GHBP Bovine is purified by proprietary chromatographic techniques. |
Source | Escherichia Coli. |
Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
Formulation | The Growth Hormone Binding Protein Bovine was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. |
Solubility | It is recommended to reconstitute the lyophilized GHBP Bovine in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
Stability | Lyophilized Growth Hormone Binding Protein Bovine although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GHBP Bovine should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Purity | Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Amino acid sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Phe-Ser-Gly-Ser. |
Usage | ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY.They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals. |
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