亚洲精品国产v片在线观看,欧美v日韩v国产综合,亚洲av片一区二区三区不卡不,日韩欧美中文在线播放

行業(yè)產(chǎn)品

  • 行業(yè)產(chǎn)品

廈門慧嘉生物科技有限公司


當(dāng)前位置：廈門慧嘉生物科技有限公司>>細胞因子>>Prospec >>FGF 21 Human, His/重組人成纖維細胞生長因子21, His

FGF 21 Human, His/重組人成纖維細胞生長因子21, His

返回列表頁
參  考  價面議
具體成交價以合同協(xié)議為準

產(chǎn)品型號

品       牌

廠商性質(zhì)代理商

所  在  地廈門市

聯(lián)系方式：陳先生查看聯(lián)系方式

更新時間：2016-02-23 13:05:07瀏覽次數(shù)：412次

聯(lián)系我時，請告知來自 環(huán)保在線

經(jīng)營模式：代理商

商鋪產(chǎn)品：9325條

所在地區(qū)：福建廈門市

聯(lián)系人：陳先生

產(chǎn)品簡介

FGF 21 Human, His/重組人成纖維細胞生長因子21, His 產(chǎn)品編號：CYT-281
產(chǎn)品規(guī)格：10μg/50μg/1mg

詳細介紹

FGF 21 Human, His/重組人成纖維細胞生長因子21, His

產(chǎn)品編號：CYT-281
產(chǎn)品規(guī)格：10μg/50μg/1mg
 

Synonyms Fibroblast growth factor 21, FGF-21.
Introduction The FGFs are a family of more than 20 small （~17–26 kDa） secreted peptides. The initial characterization of these proteins focused on their ability to stimulate fibroblast proliferation. This mitogenic activity was mediated through FGF receptors （FGFRs） 1, 2, or 3. A fourth closely related tyrosine kinase receptor （FGFR4） was able to bind the FGFs but did not lead to a mitogenic response.
FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors （FGFRs）: FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity and, except for FGFR-4, multiple splice isoforms, and FGFR-5, which lacks an intracellular kinase domain. There is growing evidence that FGFRs can be important for regulation of glucose and lipid homeostasis. The overexpression of a dominant negative form of FGFR-1 in ? cells leads to diabetes in mice, which thus implies that proper FGF signaling is required for normal ? cell function and glycemia maintenance. FGFR-2 appears to be a key molecule during pancreatic development. Moreover, FGFR-4 has been implicated in cholesterol metabolism and bile acid synthesis.
FGF-19, has been shown to cause resistance to diet-induced obesity and insulin desensitization and to improve insulin, glucose, and lipid profiles in diabetic rodents. Since these effects, at least in part, are mediated through the observed changes in metabolic rates, FGF-19 can be considered as a regulator of energy expenditure.
FGF-21 is preferentially expressed in liver, but an exact knowledge of FGF-21 bioactivity and its mode of action have been lacking to date. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity when overexpressed in transgenic mice, and lowers blood glucose and triglyceride levels when therapeutically administered to diabetic rodents.
Description Fibroblast Growth Factor -21 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 202 amino acids （29-209） and having a molecular mass of 21.6 kDa.
The FGF-21 is fused to 20 amino acid His Tga at N-terminus and purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless clear solution.
Formulation The FGF-21 His tag protein solution in 20mM Tris-HCL buffer pH-8 and 10% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.
Purity Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence MGSSHHHHHH SSGLVPRGSH MHPIPDSSPL LQFGGQVRQR YLYTDDAT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVKTSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPAPPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs,agricultural or pesticidal products, food additives or household chemicals.


您感興趣的產(chǎn)品PRODUCTS YOU ARE INTERESTED IN

環(huán)保在線 設(shè)計制作，未經(jīng)允許翻錄必究 .? ? ? Copyright(C)?2021 http://www.zuisujiong.cn,All rights reserved.

以上信息由企業(yè)自行提供，信息內(nèi)容的真實性、準確性和合法性由相關(guān)企業(yè)負責(zé)，環(huán)保在線對此不承擔(dān)任何保證責(zé)任。 溫馨提示：為規(guī)避購買風(fēng)險，建議您在購買產(chǎn)品前務(wù)必確認供應(yīng)商資質(zhì)及產(chǎn)品質(zhì)量。

會員登錄

×

請輸入賬號

請輸入密碼

=

請輸驗證碼

收藏該商鋪

請 登錄 后再收藏

提示

您的留言已提交成功！我們將在第一時間回復(fù)您~
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |