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當(dāng)前位置:上海經(jīng)科化學(xué)科技有限公司>>抗體>>流式抗體>>Anti-Mouse CD25 eFluor® 450 (Pacific Blue® replace

Anti-Mouse CD25 eFluor® 450 (Pacific Blue® replace

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產(chǎn)品型號25 ug

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所  在  地上海市

聯(lián)系方式:李小姐查看聯(lián)系方式

更新時間:2017-08-01 02:04:31瀏覽次數(shù):421次

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經(jīng)營模式:經(jīng)銷商

商鋪產(chǎn)品:183條

所在地區(qū):上海上海市

聯(lián)系人:李小姐

產(chǎn)品簡介

Host Rat
Isotype IgG2b, kappa
Reactivity Mouse
Conjugate eFluor 450
Laser Violet Laser
Emit 450 nm
Excite 405 nm
Reported Applications Flow Cytometric Analysis

詳細(xì)介紹

Description: The eBio3C7 antibody reacts with mouse CD25, the 55 kDa interleukin-2 receptor a chain (IL-2Ra). CD25 is expressed by early progenitors of the T and B lineage as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common γ chain) to form the high affinity IL-2 receptor. Binding of IL-2 to both the high and low affinity classes of the IL-2 receptor is inhibited by the 3C7 antibody. CD25 plays a role in lymphocyte differentiation and activation/proliferation. The epitopes recognized by eBio3C7, PC61.5 and eBio7D4 are all different allowing for depletion with one antibody (typically PC61.5) and subsequent detection with another CD25 antibody.


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