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Anti-Mouse CD38 PerCP-eFluor® 710

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產(chǎn)品型號25 ug

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產(chǎn)品簡介

Anti-Mouse CD38 PerCP-eFluor® 710
Also known as: ADP-Ribosyl Cyclase, Cyclic ADP-Ribose Hydrolase
Clone: 90
RUO: For Research Use Only. Not for use in diagnostic procedures.

詳細介紹

Description: The 90 monoclonal antibody reacts with the mouse CD38 molecule, an ~42 kDa type II transmembrane protein. CD38 is expressed at increasingly higher levels on B cells at each stage of B-cell differentiation, and is then down-regulated on germinal center B cells and mature plasma cells. Its expression is reported on a subpopulation of thymocytes, mature T cells, and NK cells. Crosslinking of CD38 on the surface of mature, resting B cells induces B-cell proliferation, which is enhanced by co-signals such as IL-4 and LPS. CD38, a counter-receptor for CD31, is an ectoenzyme with cyclase and hydrolase enzymatic activity and is speculated to play a role in lymphocyte activation and differentiation.