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FITC標(biāo)記的A-Raf抗體是我司為您提供的高品質(zhì)抗體，公司生產(chǎn)的每一個抗體都經(jīng)過嚴(yán)格檢測和穩(wěn)定性測試，保證了結(jié)果的準(zhǔn)確性、敏感性、特異性。公司產(chǎn)品質(zhì)量有保證，*且我司擁有完善的市場營銷體系、現(xiàn)代化管理體系和專業(yè)化物流配送系統(tǒng)，zui大程度滿足國內(nèi)外生命科研人員的產(chǎn)品需求，公司現(xiàn)經(jīng)營抗體、ELISA試劑盒、標(biāo)準(zhǔn)品、染色液、染色試劑盒、培養(yǎng)基等多種科研產(chǎn)品，歡迎前來選購！
英文名稱 Anti-A Raf/FITC
中文名稱 FITC標(biāo)記的A-Raf抗體
別名 A raf 1; A-Raf; Raf1; A Raf proto oncogene serine/threonine protein kinase; ARAF 1; ARAF; ARaf proto oncogene serine/threonine protein kinase; ARAF1; Oncogene Araf1; Oncogene PKS2; PKS 2; PKS; PKS2; Proto oncogene Pks; RAFA 1; RAFA1; Ras binding protein DA Raf; v raf murine sarcoma 3611 viral oncogene homolog; v raf murine sarcoma 3611 viral oncogene homolog 1; v raf oncogene homolog 1 (murine sarcoma 3611 virus).
說明書 100ug
研究領(lǐng)域腫瘤細(xì)胞生物免疫學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子激酶和磷酸酶
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat,
產(chǎn)品應(yīng)用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分子量 68kDa
性狀 Lyophilized or Liquid
濃度 2mg/1ml
免疫原 KLH conjugated synthetic peptide derived from human A Raf/ARAF
亞型 IgG
純化方法 affinity purified by Protein A
儲存液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.

Function:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.

Tissue Specificity:
Predominantly in urogenital tissues.

Similarity:
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
Contains 1 RBD (Ras-binding) domain.

Database links: